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Saint Louis University, a Catholic, Jesuit institution dedicated to student learning, research, health care, and service, is seeking applicants for a post-doctoral fellow in the Edward A. Doisy Department of Biochemistry and Molecular Biology, beginning in the fall of 2014. A post-doctoral position is now available in the laboratory of Dr. Youhna Ayala to study the role of RNA metabolism in neurodegeneration. A central focus of our work is to uncover the mechanisms linking TDP-43 function and structure to disease. TDP-43 is an RNA-binding protein whose aggregation is recognized as a hallmark of neurodegenerative disorders, specifically amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal lobar degeneration. Our work combines biochemical, cellular and molecular biology approaches to investigate the regulation of TDP-43 function, TDP-43-RNA interactions, and protein aggregation. Successful candidates are expected to have a Ph.D. degree in life sciences with a special emphasis on protein expression and protein biochemistry. Previous experience in the fields of RNA processing and nucleic acid-binding proteins is a plus. Preferred candidates will have recently finished their Ph.D. degrees. Applicants should also be highly self-motivated and have a strong track record of creativity and productivity. NIH standards will be used in setting the pay scale. Interested candidates must submit a cover letter, application and current curriculum vitae to https://jobs.slu.edu. Saint Louis University is an Affirmative Action, Equal Opportunity Employer and encourages nominations of an application from women and minorities.
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