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The Paine Laboratory at the College of Pharmacy at Washington State University, Spokane, WA, is seeking a motivated and experienced research scientist with a PhD degree in Pharmaceutical Sciences or a related discipline with an emphasis in drug metabolism/transport, pharmacokinetics/pharmacodynamics,
and/or analytical chemistry.
Research projects in the Paine lab are focused on advancing the understanding of mechanisms underlying natural product-drug interactions using in vitro (drug metabolism and drug transport assays), in vivo (proof-of-concept clinical studies), and in silico (pharmacokinetic/pharmacodynamic modeling and simulation) methods. Implementation of an integrative approach that combines these methods is expected to complement and support the development of best practices for natural product-drug interaction research, improve the availability of clinical information, and best inform both healthcare providers and consumers about the safe use of natural product-drug combinations.
Ideal candidates must have initiative, be highly motivated, and be able to work independently and collaboratively. Candidates should demonstrate their experience, accomplishments, and productivity via a body of scientific publications and have excellent interpersonal and project management skills. Excellent English communication skills, both verbal and written, are absolutely essential.
Duties and responsibilities include but are not limited to:
•The operation, maintenance, method development, and troubleshooting of analytical methods using HPLC/MS-MS technology.
•Experience at adhering to applicable methods, protocols, standard operating procedures (SOPs), safety standards, good laboratory practices (GLPs), and regulatory guidelines.
•Sample analysis using HPLC-MS/MS data processing and interpretation.
•Perform method troubleshooting, laboratory investigations, and data interpretation.
•Complete assigned tasks in a timely manner to achieve study timelines.
•Write, revise, and/or review methods, SOPs, and parts of reports.
•Participate actively in group dynamics/meetings, prepare publications, and develop future directions.
This position is a 12-month term appointment with the option of renewal based on progress.
Doctoral degree in Pharmaceutical Sciences or related scientific field.
Hands-on experience and proficiency with HPLC/UPLC and LC-MS/MS instrumentation (ABSciex/Shimadzu/Analyst).
Excellent understanding of chromatographic and mass spectrometric principles.
Experience in analytical method development and validation.
Experience in wet lab techniques.
Problem-solving skills, attention to detail, and ability to excel both independently and in a team-driven environment.
Understanding of fundamentals of drug metabolism/transport and pharmacokinetics.
Candidates must presently be authorized to work in the US.
Experience in the operation, maintenance, and troubleshooting of HPLC-MS/MS-based instruments, as well as experience in assay development and validation, sample analysis, and data interpretation involving HPLC-MS/MS instrumentation.
An understanding of the fundamentals of drug metabolism/transport, drug-xenobiotic interactions, pharmacokinetics/pharmacodynamics.
Experience with relevant modeling software.
The College of Pharmacy is located on Washington State University’s Health Sciences campus in Spokane. The College resides in the new Pharmaceutical and Biomedical Sciences Building, a 125,000 square-foot, state-of-the-art research and educational facility, which offers many collaborative research opportunities.
The WSU College of Pharmacy was founded in 1891, and has been accredited since 1912. We are a graduate and professional education college. Our main degree programs include the Doctor of Pharmacy (Pharm.D.) and Doctorate in Pharmaceutical Sciences (Ph.D.).
The College relocated from Pullman to the WSU Health Sciences campus in Spokane in December 2013, but has been heavily involved in the Spokane health care community since the 1970s through our internships, experiential rotations, and pharmacy residency programs. We currently have over 500 student pharmacists and graduate students, and about 2,950 alumni. As of 2015, the WSU College of Pharmacy is ranked 21st out of 138 pharmacy schools in the country according to QS World University Rankings.
WASHINGTON STATE UNIVERSITY IS AN EQUAL OPPORTUNITY/AFFIRMATIVE ACTION EDUCATOR AND EMPLOYER. Members of ethnic minorities, women, special disabled veterans, veterans of the Vietnam-era, recently separated veterans, and other protected veterans, persons of disability and/or persons age 40 and over are encouraged to apply.
WSU is committed to excellence through diversity and faculty-friendly policy action, including partner accommodation and NSF ADVANCE Institutional Transformation programs (http://www.advance.wsu.edu/).
WSU employs only U.S. citizens and lawfully authorized non-U.S. citizens. All new employees must show employment eligibility verification as required by the U.S. Citizenship and Immigration Services.
WSU is committed to providing access and reasonable accommodation in its services, programs, activities, education and employment for individuals with disabilities. To request disability accommodation in the application process, contact Human Resource Services: 509-335-4521(v), Washington State TDD Relay Service: Voice Callers: 1-800-833-6384; TDD Callers: 1-800-833-6388, 509-335-1259(f), or firstname.lastname@example.org.
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